Objective Our previous studies have demonstrated that limb ischemic preconditioning(LIP)induced brain ischemic tolerance and up-regulated the expression of p38 MAPK and ERK in hippocampal CA1 region i
Diabetes mellitus(DM)is a group of metabolic disease with symptoms of high blood sugar levels,which may worse the stroke caused injury under unclear mechanisms.
To define the factors responsible for ischemia-induced blood-brain barrier damage is first necessary before a new strategy can be developed to counter the adverse effect of ischemia-induced endothelia
Preconditioning means that a previous minor insult prepares the body to better withstand a subsequent larger insult.High mobility group box 1(HMGB1)is a reported that mediates High mobility group box
Previous study observed that Luoyutong(LYT)capsule has a definite curative effect in patients with stroke.However,nothing has been known about the underlying mechanism of LYT in protecting cerebral is
Objective The formation of glial scar impedes the neurogenesis and neural functional recovery following cerebral ischemia.Histamine showed neuroprotection at early stage after cerebral ischemia,howeve