【摘 要】
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This study was designed to investigate the influence of Mareks disease virus (MDV) and different routes of the vaccination on the immune function of erythrocytes in chickens.Specific Pathogen-free (SP
【机 构】
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College of Animal Science and Veterinary Medicine, Shanxi Agricultural University, Taigu 030801, Chi
【出 处】
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中国畜牧兽医学会第三届中国兽医临床大会
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This study was designed to investigate the influence of Mareks disease virus (MDV) and different routes of the vaccination on the immune function of erythrocytes in chickens.Specific Pathogen-free (SPF) chicks were randomly divided into a control group (C),an experimental group challenged intraperitoneally with MDV (V),a second experimental group injected intraperitoneally (IP) with CVI988/Rispens,and a third experimental group subcutaneously inoculateded (SC) with CVI988/Rispens.The number of erythrocytes was counted.The erythrocyte immune function was evaluated with red blood cell complement receptor type 1 (RBC-CR1) and red blood cell immune complex (RBC-IC) yeast rosette-forming tests.It was found that compared with the chickens from the control group,those from Group V had fewer erythrocytes.During this time,the rate of RBC-IC rosette formation was higher in Group V than in the control group.The rate of RBC-CR1 rosette formation was lower in Group V than in the control group,except on the 26th day when the number of RBC-CR1 rosettes was higher in Group V than in the control group.The rate of RBC-CR1 rosette formation and erythrocyte count was higher in Group IP than that of Group SC.The results suggest that the immune function of chicken erythrocytes was increased in the late stages,after inoculating the Mareks virus,and intraperitoneal vaccination was more effective than hypodermic inoculation in building up the immune function of chicken erythrocytes.
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