【摘 要】
：
本文总结国内法布里病患者的中枢神经系统损害的头颅核磁共振改变特点.对7例患者出现中枢神经系统临床表现的年龄在38.4±9.0岁(25～50岁),严重度评分(MSSI)为24.9±8.2分(15-37分),主要临床症状包括头晕、视物成双、走路不稳、认知功能下降、头痛、构音障碍、吞咽困难和饮水呛咳.对所有患者行经颅多普勒超声检查和头颅MRI扫描(T1WI,T2WI,T2 FLAIR和DWI),其中5例
【出 处】
：
2015北京医学会神经病学学术年会
论文部分内容阅读
本文总结国内法布里病患者的中枢神经系统损害的头颅核磁共振改变特点.对7例患者出现中枢神经系统临床表现的年龄在38.4±9.0岁(25～50岁),严重度评分(MSSI)为24.9±8.2分(15-37分),主要临床症状包括头晕、视物成双、走路不稳、认知功能下降、头痛、构音障碍、吞咽困难和饮水呛咳.对所有患者行经颅多普勒超声检查和头颅MRI扫描(T1WI,T2WI,T2 FLAIR和DWI),其中5例患者加做了T2*WI序列,统计梗死灶分布数量和部位,对头颅MRI白质病变进行评分.得出结论：法布里病的脑损害表现为脑的小卒中，具有小血管损害的特点。丘脑枕征不多见。
其他文献
Objectives To investigate the association of rs1221497 in KCNJ5 gene and primary aldosteronism (PA).KCNJ5 is a gene encoding a G-protein-coupled inwardly rectifying potassium.Methods A total of 218 PA
Objectives Doxorubicin often causes damage to the heart, which may present as cardiomyopathy.However, the mechanisms by which doxorubicin induces cardiotoxicity remain not fully understood and effecti
Objectives Using cultured myocardial cells in vitro and establishing virtual hypoxia environment of cardiomyocyte apoptosis model, to observe the expression of Rock in myocyte exposed to different hyp
Objectives Retinol binding protein 4 (RBP4)-a newly discovered adipocytokines, has been found to be associated closely with obesity, insulin resistance, cardiac vascular disease (CVD), metabolic syndr
Objectives This study was designed to test the hypothesis that PJS modulates inflammatory processes to prevent cardiac functional deterioration and reduce ventricular remodelling after MI.Methods Male
Objectives Administration of ACE inhibitor (ACEI) and AT1 receptor antagonist (AT1RA) influences ACE2 expression in the heart in myocardial infarcted rats.However, it is unclear how the expression of
本文为提高对成人肾病综合症合并脑梗死的临床特点及危险因素的认识.收集了首都医科大学宣武医院神经内科2000年以来明确诊断的成人肾病综合症合并脑梗死的病例,对其临床资料和影像学进行回顾性分析.得出结论：肾病综合症合并脑梗死以颈内动脉系统，尤其大脑中动脉供血区梗死多见，往往合并不同程度的大脑中动脉狭窄。高脂血症，高纤维蛋白血症，低蛋白血症等为肾病综合症合并急性脑梗死的常见危险因素。
本文对大脑中动脉闭塞(middle cerebral artery occlusion,MCAO)后存活患者进行长期随访,观察预后不良的影响因素,并进行分析.选取2006年1月至2013年12月在首都医科大学附属北京友谊医院住院就诊,行头颈部CT血管成像(CT angiography,CTA)或核磁血管成像(Magnetic resonance angiography,MRA)证实存在MCAO的1
本文分析单侧颈内动脉系统血管狭窄或闭塞后患者的灌注核磁表现及影响灌注受损程度的相关性因素.通过数字减影血管造影挑选出单侧颈内动脉或大脑中动脉狭窄/闭塞,且对侧颈内动脉系统无严重狭窄的老年患者33例;采集入选患者的一般临床资料;利用磁共振灌注加权成像(perfusion weighted imaging,PWI)采集入选患者的灌注参数,根据灌注损伤的严重程度分为4期,作为PWI基线资料.发现PWI在
本文为探讨短暂性脑缺血发作(TIA)患者发作间期CT灌注成像(CT perfusion,CTP)变化,为其诊断、治疗提供影像学依据.对69例TIA患者发作间期均行CTP检查,获得脑血流量(cerebral blood flow,CBF)、脑血容量(cerebral blood volume,CBV)、平均通过时间(mean transit time,MTT)、达峰时间(time to peak,T