Chemotherapy-induced alteration of SDF-1/CXCR4 expression in bone marrow derived mesenchymal stem ce

来源 :The 35th World Congress of the International Society of Hema | 被引量 : 0次 | 上传用户：foxdeng

【摘要】

：

【作者】

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Jian Ge Yan Hu Yu Gui Mingzhen Yang Qingshu Zeng Ruixiang Xia

【机构】

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The First Affilated Hospital of Anhui Medical University

【出处】

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The 35th World Congress of the International Society of Hema

【发表日期】

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2014年5期

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Background Bone marrow derived-mesenchymal stem cells (BM-MSCs) in the marrow stroma provide a framework of microenvironment niches and release chemokines to modulate hematopoiesis in vivo.Chemokine stromal cell-derived factor-1 (SDF-1) and its receptor CXCR4 have been shown to affect the engraftment of hematopoietic stem cells.

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Chemotherapy-induced alteration of SDF-1/CXCR4 expression in bone marrow derived mesenchymal stem ce

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