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Introduction: An evidence-based formula of Frontal integration (NeM) [Larsen, 2010] may be used to assess options, of optimization calculating the first derivative: dC/dc =2Rc/L (x)where C is the Frontal Power-of concentration, R is a constant indicating semantic knowledge (STS), c is the attention (vmPFC) and L (x) is the degree of Limbic arousal.The study aims to verify operational properties of dC/dc.Method: c is operated as an evoked response potential (P300) in the EEG alpha band and L (x) is operated as baseline electrodermal activity (EDA).Systematic literature search of c/L (x) uncover more studies, whereof the key references are:· Larsen T: Neuroeconomics and Public Health, Acta Systemica 2010, Vol-No 1 · Gountas J, Ciorciari J: Inside the Minds of the Trendsetters.Australian Magazine Sci/Tech, May 2010 · Sequeira H et al: Brain-body Impact of Emotion.NeuroTalk 2011, p.81.BIT Lifesciences.Results:(1) c and L (x) are negatively correlated as predicted by NeM (2) c/L (x) is a discrete variable with three different clusters around hyper-, medium-and hypo-responders (3) Four different consumer-profiles rooted in neural patterns are identified: (a) Rationalist (dlPFC), (b) Conscientious (OFC), (c) Pragmatic (Amygdala) and (d) Imaginative (Ins/ACC) Discussion: In real life four different coping patterns exist while only three of them seem directly identified by neurological studies.However, this problem is due to the variability of group (d) which over time may shift from one neurological pattern to another.Conclusion: Empirical verification of the first derivative of NeM uncovers four different coping patterns within the pattern of normal behaviors: Rationalists ~ Hyper-responders dominated by dlPFC, Conscientious-oriented ~ Medium responders dominated by OFC, Pragmatics ~ Hypo-responders dominated by Amygdala and Imaginatives ~ Shifting response-pattern dominated by Ins/ACC.In summary, differentiating neurodynamics by temper opens a new evidence-based pathway for training programs to improve broad objectives as team building, personal health promotion and creative thinking.