Lipid in T-cell receptor transmembrane signaling

• 作 者: Hua Li Xingdong Guo Chengsong Yan Xiaoshan Shi Catherine Wong James J.Chou Yi Cao Chenqi Xu
• 机 构: National Center for Protein Science Shanghai,State Key Laboratory of Molecular Biology,Institute of
• 出 处: 第十四次全国暨国际生物物理大会
• 发表日期: 2015年3期
• 关键词: T-cell receptor lipid conformational dynamics

　　T-cell receptor-CD3 complex(TCR) is a versatile signaling machine that can trigger immune responses in an antigen-specific manner,based on the various biochemical changes of CD3 cytoplasmic domains.