慢性乙型肝炎的联合治疗

• 作 者: 徐克成 吴建文
• 机 构: 深圳市罗湖人民医院肝病研究中心!518001、深圳养和医疗中心,Department of Internal Medicine,Louisiana State University School of
• 出 处: 胃肠病学
• 发表日期: 2001年02期
• 关键词: 慢性乙型肝炎 治疗慢性乙肝 药物联合应用 抗病毒治疗 作用机制 研究方向 临床研究 联合用药 证明 实验 方法

２０世纪最后１０年内，乙型肝炎病毒（ＨＢＶ）感染的治疗取得了重大进展，抗病毒治疗地位的确定以及α－干扰素（ＩＦＮ－α）和新核苷拟似药的应用改善了慢性ＨＢＶ感染的自然病史和预后。但现有的抗病毒治疗尚存在以下问题［１］：第一，难以根除病毒。ＨＢＶ基因组在肝细?

Significant advances have been made in the treatment of hepatitis B virus (HBV) infections in the last decade of the 20th century, and the identification of antiviral treatment status and the use of interferon-alpha (IFN-α) and novel nucleoside quasi-drugs improve chronic HBV Natural history and prognosis of infection. However, the existing antiviral therapy still has the following problems [1]: First, it is difficult to eradicate the virus. HBV genome in liver fine?