Combretastatin A4 induces impairment of endothelial cells function and inhibits angiogenesis by inhi

• 作 者: Min Su Xiaoyan Yang Kunjian Peng Suyou Liu Zhiyong Luo
• 机 构: Molecuar Biology Research Center,State Key Laboratory of Medical Genetics,School of Life Sciences,Ce
• 出 处: 中国植物学会第十四届全国药用植物及植物药学术研讨会
• 发表日期: 2016年3期
• 关键词: Combretastatin A-4 Anti-angiogenesis human umbilical endothelial cells VEGF VEGF

　　the formation of new blood vessels by endothelial cells from existing microvessels,is a critical process in solid tumor.Accordingly,the inhibition of angiogenesis is considered to be a promising strategy of treating cancer.In the present study,we tested the anti-angiogenic effect and mechanism of Combretastatin A-4(CA4).