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  5. The Study of Bi-lineage Differentiated ADSCs Sheet to Improve Implant Osseointegration in the Irradi

The Study of Bi-lineage Differentiated ADSCs Sheet to Improve Implant Osseointegration in the Irradi

来源 :2014xi`an Conference of International Society for Maxillofac | 被引量 : 0次 | 上传用户：wangchaohui
【摘 要】
：
Purpose: To evaluate the effect of osteogenic and angiogenic bi-lineage differentiated adipose tissuederived stem cells(ADSCs)sheet on implant osseointegration in the irradiated bone.Methods: The lowe
【作 者】
：
Dong Yan Ren Nan Zhou Wei Liu Huan Zhao Yimin 
【机 构】
：
Department of Prosthodontics,School of Stomatology,Fourth Military Medical University
【出 处】
：
2014xi`an Conference of International Society for Maxillofac
【发表日期】
：
2014年4期
【关键词】
：
Adipose tissue-derived stem cells Cell sheet Implant Radiotherapy Osseointegrati 
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　　Purpose: To evaluate the effect of osteogenic and angiogenic bi-lineage differentiated adipose tissuederived stem cells(ADSCs)sheet on implant osseointegration in the irradiated bone.Methods: The lower hindlimbs of rats had external irradiation of a single dose of 20Gy.Eight weeks later,osteogenic and angiogenic bi-lineage differentiated ADSCs sheet-implant complex(Group A)was implanted in the tibia of the irradiated rat.Osteogenic differentiated ADSCs sheet-implant complex(Group B)and traditional pure Ti implant(Group C)were served as control groups.After eight weeks of implantation,Micro CT assay were conducted in vivo.Then the pull-out tests were proceeded and the rest of specimens were utilized to make hard tissue slices to analyze the implant osseointegration.
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