论文部分内容阅读
High-density lipoprotein (HDL) with lipid accumulation may have pro-inflammatory effects to the endothelial cells, which causes atherosclerosis in type 2 diabetes mellitus (T2DM).HDL is the major lipoprotein that harbors sphingosine-l-phosphate (S1P) in plasma and S1P is important in various biological functions.