CRKL suppression decreases the proliferation,invasion and imatinib resistance of CML cells

来源 :中国生物化学与分子生物学会2019年全国学术会议 | 被引量 : 0次 | 上传用户：hotjune

【摘要】

：

BCR-ABL kinase activation triggers the downstream signaling molecules including phosphoinositide 3-kinase(PI3K)/Akt,FAK/Src,STAT5 and c-MYC.

【作者】

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Ming-Zhong Sun Guoping Shi Shuqing Liu

【机构】

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Department of Biotechnology,Dalian Medical University,Dalian,116044

【出处】

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中国生物化学与分子生物学会2019年全国学术会议

【发表日期】

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2019年10期

【关键词】

：

CML CRKL proliferation migration invasion apoptosis

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　　BCR-ABL kinase activation triggers the downstream signaling molecules including phosphoinositide 3-kinase(PI3K)/Akt,FAK/Src,STAT5 and c-MYC.

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CRKL suppression decreases the proliferation,invasion and imatinib resistance of CML cells

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