An open, multi-center, phase Ⅱ clinical trial to evaluate the efficacy and safety of S-1 plus splitd

来源 :22nd Asia Pacific Cancer Conference(第22届亚太抗癌大会) | 被引量 : 0次 | 上传用户:sdqzdx
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Objective: The SPIRITS trial indicated that S-1 plus cisplatin can be regarded as standard first-line chemotherapy for patients with advanced gastric cancer (AGC) in Japan (Koizumi W,et al.Lancet Oncol, 2008).However, the conventional S-1plus cisplatin regimen requires hospitalization for hydration.Therefore, in Hokkaido Gastrointestinal Cancer Study Group(HGCSG), we conducted a multicenter phase Ⅱ clinical trial to investigate the safety and efficacy of administering S-1 plus splitdose in outpatient clinics.
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