Enhanced circulating ILC2s and MDSCs in patients with lung cancer accompanied by a predominant Th2 p

来源 :中国免疫学会第九届全国免疫学学术大会 | 被引量 : 0次 | 上传用户:zhouf
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BACKGROUND: Group 2 innate lymphoid cells (ILC2s) were shown to be involved in the initiation and coordination of Th2-type immune responses.Myeloid derived suppressor cells (MDSCs) have received a great deal of attention for their role in creating an immunosuppressive microenvironment in cancer bearing hosts.We have found that there was a dramatically enhanced ILC2s in peripheral blood in gastric cancer.However, the contributions of ILC2s and MDSCs in the occurrence and development of lung cancer, and the correlation between circulating Th2 cells and ILC2s or MDSCs in patients with lung cancer remain unclear.
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