【摘 要】
：
Difunctionalization alkenes presents one of the most powerful methods available for the regioselective formation C-C bonds.Recently, our efforts were focused on
【机 构】
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ShanghaiInstituteofOrganicChemistry,CASShanghai200032
【出 处】
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中国化学会全国第十一届有机合成化学学术研讨会
论文部分内容阅读
Difunctionalization alkenes presents one of the most powerful methods available for the regioselective formation C-C bonds.Recently, our efforts were focused on the catalytic difunctionalization of C=C bonds utilizing transition metal, in which high-valent metal intermediate was proven to be important for the C-X bond formation.[1,2] We found that some special chemical bonds were achieved from high-valent metal center in the presence of weak nucleophiles, such as C-F bond from fluoride ion, C-OH bond from water.In addition, the fmal oxidative cleavage C-M bonds were demonstrated as slow step.Based on these observations, the more challenging intermolecular difunctionalization of olefins was also further explored.
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