Foxp3+ Regulatory T (Treg) cells harbor immune suppressive capacities and are crucial for the maintenance of immune homeostasis and control of dominant immu
Background:Chronic hepatitis B virus (HBV) infection is characterized by continuing liver inTo investigate the mechanisms which co-inhibitory pathway mediat
Objective: To investigate the synergic role of TGF-β and IL-2 in regulating the balance between the regulatory T cells and conventional T cells, thus the h
Background: Natural killer (NK) cell plays critical roles in anti-tumor immunity.T cell immunoglobulin and mucin domain-3 (Tim-3) is a well-known immune med
RATIONALE: Idiopathic pulmonary fibrosis (IPF) is a highly heterogeneous and lethal pathological process with limited therapcutic options, which is the most
p38 mitogen-activated protein kinase (MAPK) activity has been reported to either promote or suppress cell death, which depends on cell type and stimulus.