Design,synthesis and antifungal activity of Benzofuran derivatives as N-myristoyltransferase inhibit

来源 :2015年全国药物化学学术会议暨第五届中英药物化学学术会议 | 被引量 : 0次 | 上传用户：littlev19

【摘要】

：

Benzofuran derivatives(2)have been proved to be antifungal agents targeting fungal N-myristoyltransferase(NMT)with high selectivity between fungi and human[1].

【作者】

：

Zhen Liang Ye Tian Mengbi Guo Chan Li Yukun Hu Chun Guo

【机构】

：

Key Laboratory of Structure-Based Drug Design & Discovery(Shenyang Pharmaceutical University),Minist

【出处】

：

2015年全国药物化学学术会议暨第五届中英药物化学学术会议

【发表日期】

：

2015年3期

【关键词】

：

Antifungal N-myristoyltransferase inhibitors Semicarbazide Thiosemicarbazide

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　　Benzofuran derivatives(2)have been proved to be antifungal agents targeting fungal N-myristoyltransferase(NMT)with high selectivity between fungi and human[1].

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Design,synthesis and antifungal activity of Benzofuran derivatives as N-myristoyltransferase inhibit

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