【摘 要】
：
Cell-penetrating peptides (CPPs) are short, often hydrophilic peptides that can deliver biologically active molecules into ceils and that are likely to play
【机 构】
：
Chongqing Engineering Technology Research Centre of Veterinary Drug,College of Pharmaceutical Scienc
【出 处】
：
2014年中国药物制剂大会——中国药学会药剂专业委员会年会、第六届亚洲阿登制药技术研讨会暨国际控释协会中国分会年会
论文部分内容阅读
Cell-penetrating peptides (CPPs) are short, often hydrophilic peptides that can deliver biologically active molecules into ceils and that are likely to play a key role in the development of future biotherapeutics.However, the application of the CPPs is limited because the transduction efficiency is often insufficient and the cellular localization is unpredictable.We investigated the effects of a penetration enhancer, 1,2-Benzisothiazolin-3-One (BIT), on the uptake of a synthetic fluorescent TAT and a TAT-conjugated Green fluorescent protein or the pro-apoptotic peptide KLA, and evaluated its toxicity in various cell lines.
其他文献
高职高专会计教育是我国高等学校会计教育不可或缺的组成部分,本文在分析高职高专会计教学现状的基础上,提出一些改进的措施。
Accounting education in higher vocational
The purpose of this research was to study effects of butyl stearate (BS) on in vitro drug release of carboxyl terminal and ester end-capping PLGA-based tolt
《国务院关于基础教育课程的改革与发展的决定》要求:课程改革倡导学生主动参与、乐于探究、勤于动手,培养学生收集和处理信息的能力、获取新知识的能力、分析问题的能力以及
THE Fourth China International Clothing & Accessories Fair and Brother Cup China International Young Fashion Designers Contest were held in Beijing in mid-Apri
The central dogma of drug delivery is to steer therapeutic cargos to target tissues and/or cells to achieve maximal therapeutic efficacy with minimal toxic