A.Flavus Mediated Biotransformations for the Syntheses of Active A-oxyfunctionalized Compounds

• 作 者: P.Ayhan S.Betul Sopaci A.S.Demir
• 机 构: Department of Biotechnology Middle East Technical University,Department of Biotechnology Middle Eas
• 出 处: 复旦学报(自然科学版)
• 发表日期: 2007年05期

1 Results Biotransformations are enzyme- and whole cell-catalysed conversions of non-natural substrates to products.They are important tools in organic synthesis,especially for the syntheses of chiral molecules,where the reactions catalysed may be asymmetric syntheses or the resolution of racemates.The main advantages associated with the use of single enantiomer compounds are increased specificity and the avoidance of adverse side effects[1].Whole cell reactions are advantegous over enzyme-catalyzed reactions as they are lest costly and no cofactors are needed.While with the later less by-products are obtained.

1 Results Biotransformations are enzyme- and whole cell-catalysed conversions of non-natural substrates to products. They are important tools in organic synthesis, especially for the syntheses of chiral molecules, where the reactions catalysed may be asymmetric syntheses or the resolution of racemates. The main advantages associated with the use of single enantiomer compounds are increased specificity and the avoidance of adverse side effects [1] .Whole cell reactions are advantegous over enzyme-catalyzed reactions as they are lest costly and no cofactors are needed. Whilst with later less by-products are obtained.