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Purpose: Edentulous patients after hemimaxillectomy always have difficulties in retention and stability when applicated with conventional complete denture,due to the lost of teeth,the reduction of supporting alveolar and neuromuscular disorder.Thus,implant-supported overdentures with Locator attachment are recommended.We report the case of application of implant-supported overdenture with Locator attachment in an edentulous patient after hemimaxillectomy.