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Objective: We evaluated the effects of Seoritae extract (SE) on mild-to-moderate lower urinary tract symptoms (LUTS) suggestive of benign prostatic hyperplasia (BPH).Methods: Seventy-six subjects with mild to moderate LUTS suggestive of BPH were prospectively recruited from the urology outpatient clinic,and assigned to either SE (4,200 mg or 6 tablets 3 times a day) or matching placebo.