Genetic Polymorphisms in Cyclooxygenase-2 are Associated with Radiotherapy Response and Survival in

• 出 处: 中国抗癌协会肿瘤放射治疗专业委员会学术大会、中美放射肿瘤协会第三届学术会议、2012济南国际放射肿瘤学论坛
• 发表日期: 2012年期

Purpose：COX-2 plays important roles in modulation of immune response,apoptosis,angiogenesis,and tumor invasion．COX-2 expression was reported to correlate with survival after radiotherapy and the response to radiotherapy．This study investigated whether genetic variations in COX-2 gene are associated with radiotherapy response and the survival in esophageal squamous cell carcinoma(ESCC)patients treated with preoperative radiotherapy．