【摘 要】
：
In the biological world,the hydrophobic phospholipid bilayers maintain the distinction between a normal and a cancer cell.Specific activities of these cells
【机 构】
：
University of Notre Dame USA
【出 处】
：
中国上海第七届国际新药发明科技年会
论文部分内容阅读
In the biological world,the hydrophobic phospholipid bilayers maintain the distinction between a normal and a cancer cell.Specific activities of these cells are also maintained by active participations of specific proteins,proteoglycans (PGs),glycoproteins (GPs),glycosphingolipids (GSLs),and glycerophosphoinositol-glycolipids (GPIGs) on the surfaces.Although we understand now the complete biosynthetic pathways of some GSLs,the functions of glycosphingolipids on the eukaryotic cell membranes during the onset of oncogenic processes and cell death are not well understood.Inhibitors of glycosphingolipid biosynthesis (L-PPMP and D-PDMP) and DNA-biosynthesis inhibitor (cis-platin) were recently found to trigger apoptosis in human breast carcinoma cells (SKBR-3,MCF-7,and MDA-468) through either intrinsic or extrinsic apoptotic pathways.
其他文献
去年以来,阆中市社保局以“创满”、“争满”为契机,广泛展“争创一流”社保局、创“满意单位”及“三优文明窗口”活,努力在“求实、求深、求新”和“便民、为民、安民”上
物业管理不再是“免费的午餐”,如何让收费更加透明成为物业公司与业主都关心的焦点问题。
Property management is no longer a “free lunch,” and how to make fees mor
The active site of potassium (K+) channels catalyses the transport of K+ ions across the plasma membrane and is inhibited by toxins from various venomenous
一、控制枝梢旺长 ,防止果园郁闭油桃分枝能力强 ,易抽生二次枝甚至三次枝 ,加之油桃树势旺 ,特别是未结果前的幼树期及采果后由于果实对新梢的抑制作用减弱 ,极易发生徒长。
During the past two decades, my process research group is involved in the development of a truly efficient, reliable, greener and economically viable synthesis
目的观察下肢动脉硬化闭塞症(ASO)患者经Silverhawk斑块旋切系统联合药物涂层球囊(DCB)治疗的临床效果，探讨未来ASO治疗方案的优化。方法抽取2018年1月至2019年6月郑州人民医院及郑州大学第五附属医院接受治疗的ASO患者142例，采用数字奇偶法将纳入患者分为观察组(偶数)和对照组(奇数)，每组71例。对照组接受常规治疗联合DCB治疗，观察组在对照组基础上联合Silverhawk斑
How representative are the current preclinical angiogenesis models for the clinical setting.As tumor growth is angiogenesis dependent,angiogenesis is a targ