论文部分内容阅读
Synthesis, biological evaluation and molecular modeling of quinazoline/pyrimidine-2,4(1H,3H)-dione d
【机 构】
:
College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058,China
【出 处】
:
2016年长三角药物化学研讨会
【发表日期】
:
2016年11期
其他文献
Cancer metastasis is the major cause of cancer-associated death[1].The molecular mechanism is complex,involving the change of multi-step,multi-stage and multi-gene.Based on biological testing of tumor
The FDA approval of the peptide-based proteasome inhibitors bortezomib,carfilzomib,and ixazomib in 2003,2012,and 2015,respectively,has validated the proteasome as an important target in the treatment
The Design, Synthesis and Biological Evaluation of Pro-EGCG Derivatives as Novel Anti-vitiligo Agent
With aim to overcome the instability and poor membrane permeability of EGCG,1 a series of prodrugs of EGCG and its derivatives (Pro-EGCGs) were designed,synthesized,and biological evaluation for their
Curcumin analogue L48H37 induces apoptosis through ROS-mediated endoplasmic reticulum stress and STA
会议
会议
Chlorin p6-based Water-soluble Amino Acid Derivatives as Potent Photosensitizers for Photodynamic Th
The development of novel photosensitizer with high phototoxicity,low dark-toxicity and good water solubility is a challenging task for photodynamic therapy (PDT).A series of chlorin p6-based water-sol
会议
Evidence is accumulating that high levels of nitric oxide (NO) could act as a cytotoxic and apoptosis-inducing agent against tumor cells.[1]Diazeniumdiolates derived from secondary amines usually act
会议