HBeAg阳性慢性乙型肝炎应用恩替卡韦联合CIK免疫治疗的临床研究

来源 :中华医学会第五次全国病毒性肝炎慢性化、重症化基础与临床研究进展学术会议 | 被引量 : 0次 | 上传用户：chengleitao

【摘要】

：

目的:探讨恩替卡韦联合细胞因子诱导的杀伤细胞(CIK)治疗HBeAg阳性慢性乙型肝炎(CHB)的临床疗效及安全性.方法:收集50例HBeAg阳性CHB患者,其中治疗组20例,采用恩替卡韦联合CIK治疗,对照组30例,单用恩替卡韦治疗.观察所有患者治疗前及治疗后第12、24、48周肝功能、HBV血清标志物和HBV DNA水平并进行统计学分析,同时对不良反应进行评估.

【作者】

：

黄文琪许金超王少扬闵峰邱育淼洪美珠吴卫兵叶会丽范荣华张丽李柏丽

【机构】

：

中国人民解放军第174医院感染科南京军区福州总医院感染科

【出处】

：

中华医学会第五次全国病毒性肝炎慢性化、重症化基础与临床研究进展学术会议

【发表日期】

：

2015年11期

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

其他文献

Highly expression of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and its recepto

AIMS: High expression and activation of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) on natural killer (NK) cells could mediate hepatocyte apoptosis in patients with chronic hepatit

会议

Serum Thyroid hormone levels in patients with acute-on-chronic liver failure caused by hepatitis B v

Objective: It has been increasingly evident that several conditions other than thyroid disease change the concentrations of thyroid hormones.Many studies have demonstrated that severe systemic nonthyr

会议

An analysis of risk factors of secondary infection of patients with HBV related acute-on-chronic liv

Aims : The aim of this study is to evaluate its impact on clinical outcome and identify the potential risk factors for its development in these patients.Methods : In this retrospective and case contro

会议

The epoxyeicosatrienoic acids ameliorated liver inflammation in mice with steatohepatitis by inhibit

Background and aims : Nonalcoholic steatohepatitis (NASH) may progress to endstage liver disease and hepatocellular carcinoma.The epoxyeicosatrienoic acids (EETs), the products of cytochrome P450 epox

会议

Hsa-miR-181c was significantly down-regulated in PBMC of acute-on-chronic liver failure patients cau

Aim : A lot of research shows hepatocyte apoptosis induced by TNF-α/TNFR1 or Fas/FasL and high expression of IFN-γ are important pathway for the incidence of fulminant viral hepatitis.

会议

Improved function of natural killer cells correlates with seroconversion of hepatitis b envelope ant

Aims: Natural killer (NK) cells play pivotal roles in the control and clearance of hepatitis B virus (HBV) in chronically infected patients.This study aimed to investigate the dynamic changes of NK ce

会议

Tenofovir Disoproxil: Effective and Safe in Prevention of Mother-to-child Transmission of Hepatitis

Background Mother-to-child transmission (MTCT) of hepatitis B virus (HBV) still remains a world concerned question.Previous studies have demonstrated the effectiveness of telbivudine (LdT) and lamivud

会议

Association between polymorphisms of sodium taurocholate cotransporting polypeptide gene and phonoty

Backgrounds and aims: Sodium taurocholate cotransporting polypeptide (NTCP, encoded by SLC10A1), a multiple transmembrane transporter predominantly expressed in the liver, was found as a functional re

会议

肝硬化急性肾损伤的诊断与处理--国际腹水俱乐部2014共识介绍

急性肾损伤概念的变迁·1796年Morgagni提出了"少尿"的概念·1900年古希腊医学家Galen发现了患者突然无尿的现象,称其为尿闭症(ischuria),并将其分为膀胱充盈型及膀胱空虚型,而后者被认为是对AKI最早的认识·"ARF"的概念于1951年首次正式提出·2002年以来提出了AKINatural history of cirrhosis

会议

The difference of serum cytokines expression between HBeAg-positive and HBeAg-negative chronic hepat

Background & Aims: The pattern of cytokines in sera was consistent with the level of inflammation during chronic hepatitis.By observing the difference of cytokines expression between HBeAg-positive an

会议

HBeAg阳性慢性乙型肝炎应用恩替卡韦联合CIK免疫治疗的临床研究

其他学术论文