HIF1 alpha Is Required To Switch On GATA1 Expression During Primitive Erythropoiesis

来源 :2015亚太发育生物学国际研讨会 | 被引量 : 0次 | 上传用户：zhuoluo

【摘要】

：

During embryonic development, the erythrocytes are generated from two waves of hematopoiesis.In zebrafish, the primitive wave occurs in ICM and the definitive w

【作者】

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Bo-An Lin Jyuan-Kai Chiou Yi-Xuan Lin Kun-Tong Chiu Wen-Shyong Tzou Chin-Hwa Hu

【机构】

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DepartmentofBioscienceandBiotechnology,NationalTaiwanOceanUniversity2,Pei-NingRoad,Keelung,Taiwan

【出处】

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2015亚太发育生物学国际研讨会

【发表日期】

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2015年9期

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During embryonic development, the erythrocytes are generated from two waves of hematopoiesis.In zebrafish, the primitive wave occurs in ICM and the definitive wave of hematopoiesis occurs in AGM.The transcription factors that regulate erythrocyte specification are all expressed in the hemangioblasts at 2 somite stage.After commitment, the GATA factor is switched from GATA2 to GATA1, a process referred to as GATA factor switching.

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HIF1 alpha Is Required To Switch On GATA1 Expression During Primitive Erythropoiesis

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