论文部分内容阅读
Oxaliplatin,Pt(R,R-DACH)(oxalate),is a third-generation platinum derivative,which is one of the most effective drugs for metastatic colorectal cancer[1].The anticancer activity of oxaliplatin arises from its ability to damage DNA,with the major adducts formed being intrastrand d(GpG)and d(ApG)crosslinks.