Nigrostriatal dopamine acting on globus pallidus regulates sleep

来源 :The 6th FAONS Congress and 11th Biennial Conference of CNS(第 | 被引量 : 0次 | 上传用户：doer

【摘要】

：

Lesions of the globus pallidus externa(GPe)produce a profound sleep loss(~45%)in rats,suggesting that GPe neurons promote sleep.As GPe neuronal activity is enhanced by dopamine(DA)from the substantia

【作者】

：

Mei-Hong Qiu Qiao-Ling Yao Ramalingam Vetrivelan Michael C Chen Jun Lu

【机构】

：

State key Laboratory of Medical Neurobiology and Department of Neurobiology,School of Basic Medical

【出处】

：

The 6th FAONS Congress and 11th Biennial Conference of CNS(第

【发表日期】

：

2015年3期

【关键词】

：

dopamine sleep substantia nigra pars compacta globus pallidus Parkinson’s diseas

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　　Lesions of the globus pallidus externa(GPe)produce a profound sleep loss(~45%)in rats,suggesting that GPe neurons promote sleep.As GPe neuronal activity is enhanced by dopamine(DA)from the substantia nigra pars compacta(SNc),we hypothesized that SNc DA via the GPe promotes sleep.

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Nigrostriatal dopamine acting on globus pallidus regulates sleep

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