Metabolic Activation of Furan Moiety Makes Diosbulbin B Hepatotoxic

来源 :2015第11届全国药物和化学异物代谢学术会议 | 被引量 : 0次 | 上传用户：hll10

【摘要】

：

Diosbulbin B (DIOB), a furanoid, is a major constituent of herbal medicine Dioscorea bulbifera L.Exposure to DIOB caused liver injury in humans and experimental animals.

【作者】

：

Weiwei Li Dongju Lin Huiyuan Gao Youjun Xu Dongya Meng Charles Vincent Smith Ying Peng Jiang Zheng5

【机构】

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Key Laboratory of Structure-Based Drug Design and Discovery of Ministry of Education

【出处】

：

2015第11届全国药物和化学异物代谢学术会议

【发表日期】

：

2015年9期

【关键词】

：

Diosbulbin B Metabolic activation Hepatotoxicity

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　　Diosbulbin B (DIOB), a furanoid, is a major constituent of herbal medicine Dioscorea bulbifera L.Exposure to DIOB caused liver injury in humans and experimental animals.

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Metabolic Activation of Furan Moiety Makes Diosbulbin B Hepatotoxic

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