【摘 要】
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Temperature of live cells is one of the basic parameters for studies in cell biology,cellular pathogenesis of cancers and other diseases,as well as in many clinical practices.However,to precisely meas
【机 构】
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Key Laboratory for the Physics & Chemistry of Nanodevices,School of of Electronics Engineering and C
【出 处】
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中国微米纳米技术学会纳米科学技术分会第四届年会暨2016国际纳米生物与医学学术会议
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Temperature of live cells is one of the basic parameters for studies in cell biology,cellular pathogenesis of cancers and other diseases,as well as in many clinical practices.However,to precisely measure the temperature distribution in individual live cell remains a technical challenge.Several non-contact methods using fluorescent nano-thermometers have been developed for detecting the temperatures of live cells at the sub-cell level and nanoscale,where nano-indicators of quantum dot,polymer particle,nano-diamond,protein and organic dye are pre-injected into live cells,and the change in intensity,peak position or lifetime of the luminescence spectra of the nano-indicators under external lights are used to calculate the change of local temperatures [1,2].
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