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  5. Smart Albumin-Biomineralized Nanocomposites for Multimodal Imaging and Photothermal Tumor Ablation

Smart Albumin-Biomineralized Nanocomposites for Multimodal Imaging and Photothermal Tumor Ablation

来源 :The 6th International Conference on Nanoscience and Technolo | 被引量 : 0次 | 上传用户：cyf1122
【摘 要】
：
Multimodal imaging-guided cancer therapy dramatically advances the new field of cancer theranostics.Nevertheless,so far smart theranostic agents have been explored with limited success for multimodal
【作 者】
：
Yong Wang Tao Yang Hengte Ke Huabing Chen 
【机 构】
：
School of Radiation Medicine and Protection,Soochow University
【出 处】
：
The 6th International Conference on Nanoscience and Technolo
【发表日期】
：
2015年5期
【关键词】
：
nanocomposite biomineralization multimodal imaging photothermal therapy tumor ab 
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　　Multimodal imaging-guided cancer therapy dramatically advances the new field of cancer theranostics.Nevertheless,so far smart theranostic agents have been explored with limited success for multimodal imaging-guided tumor ablation.Herein,we report smart cyanine-grafted gadolinium oxide nanocrystals(Cy-GdNCs)as cancer-targeted nanocomposites through albumin-based biomineralization strategy for trimodal near-infrared fluorescence/photoacoustics/magnetic resonance imaging and pH-responsive photothermal tumor ablation.[1-2]The nanocomposites exhibit remarkable trimodal imaging features with high imaging sensitivity,precise anatomical localization,and enhanced spatial resolution for comprehensive tumor detection and treatment guidance.
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