【摘 要】
：
目的 研究新生儿抗生素使用策略由风险评估策略改为风险评估加感染筛查及监测策略后住院新生儿抗生素使用率的变化以及对新生儿结局的影响,为如何进一步规范新生儿抗生素使用探寻科学依据.方法 采用队列研究,2010年1月1日～2011年05月31日,在我科住院的新生儿共4406例,为对照组,按照风险评估策略使用抗生素；2011年7月1日～2012年10月31日,在我科住院的新生儿共4476例,作为观察组,按
【机 构】
：
四川大学华西第二医院儿科,四川 成都 610041
【出 处】
：
庆祝中国当代儿科杂志创刊15周年大会暨当代儿科论坛
论文部分内容阅读
目的 研究新生儿抗生素使用策略由风险评估策略改为风险评估加感染筛查及监测策略后住院新生儿抗生素使用率的变化以及对新生儿结局的影响,为如何进一步规范新生儿抗生素使用探寻科学依据.方法 采用队列研究,2010年1月1日～2011年05月31日,在我科住院的新生儿共4406例,为对照组,按照风险评估策略使用抗生素；2011年7月1日～2012年10月31日,在我科住院的新生儿共4476例,作为观察组,按照风险评估加感染筛查及监测策略使用抗生素.分别对比两组患儿抗生素使用率、平均住院日、再入院率、死亡率.结果 住院新生儿抗生素应用策略改变后住院新生儿抗生素使用率明显降低(79.6％ vs 50.5％,P＜0.01)；患儿的平均住院日,再入院率,死亡率差异无统计学意义.结论 将住院新生儿抗生素应用策略由风险评估策略改为风险评估加感染筛查及监测策略,对于住院新生儿合理使用抗生素意义重大,能够明显减少抗生素使用率,而且不会对患儿产生不良影响.
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