Salvianolic acid B prevents arsenic trioxide-induced cardiotoxicity in vivo and enhances Its antican

来源 :The 12th Meeting of the Asia Pacific Federation of Pharmacol | 被引量 : 0次 | 上传用户：yubil

【摘要】

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【作者】

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Min WANG Gui-bo SUN Rong-chang CHEN Meng QIN Yun LUO Hong SUN Qiang ZHANG Xi DONG Xiao-bo SUN

【机构】

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Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine,Ministry

【出处】

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The 12th Meeting of the Asia Pacific Federation of Pharmacol

【发表日期】

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2013年4期

【关键词】

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salvianolic acid B arsenic trioxide cardioprotection anticancer activity

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Aim: Clinical attempts to reduce the cardiotoxicity of arsenic trioxide (ATO) without compromising its anticancer activities remain to be an unresolved issue.In this study, we determined whether Salvianolic acid B (Sal B) can protect against ATOinduced cardiac toxicity in vivo and increase the toxicity of ATO toward cancer cells.

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Salvianolic acid B prevents arsenic trioxide-induced cardiotoxicity in vivo and enhances Its antican

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