TOR in Brain Aging and Age-Associated Neurological Disease

来源 :2014 International Conference on Aging and Disease(2014年第一届衰 | 被引量 : 0次 | 上传用户：jeffyi2009

【摘要】

：

We recently showed that chronic treatment with the target-of-rapamycin (TOR) inhibitor rapamycin, a drug that extends lifespan and delays aging in mice, halted and even reversed Alzheimer s (AD)-like

【作者】

：

Veronica Galvan Ai-Ling Lin Stacy Hussong Jordan Jahrling Nick DeRosa Reto Asmis Matthew J Hart Steven Austad Kathleen Fischer

【机构】

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Department of Physiology,University of Texas Health Science Center at San Antonio,San Antonio,TX,USA

【出处】

：

2014 International Conference on Aging and Disease(2014年第一届衰

【发表日期】

：

2014年7期

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　　We recently showed that chronic treatment with the target-of-rapamycin (TOR) inhibitor rapamycin, a drug that extends lifespan and delays aging in mice, halted and even reversed Alzheimer s (AD)-like memory deficits and reduced Aβ accumulation in brains of hAPP(J20) mice modeling the disease.

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TOR in Brain Aging and Age-Associated Neurological Disease

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