3beta-hydroxysteroid-delta24 reductase (DHCR24) is a multifunctional enzyme with anti-apoptotic and cholesterol-synthesizing activities and localizes to endoplasmic reticulum.
Stressful experiences, especially psychological stress, can precipitate depression disorder, which is a common public health problem.Accumulating evidence implicates hippocampal neurogenesis in the pa
Pituitary adenylate cyclase-activating polypeptide (PACAP) regulates synaptic plasticity and is related to control of emotion and other central nervous system functions.
The complete cDNA sequence of a novel gene, spinal cord injury and regeneration related gene No.69 (SCIRR69) obtained by RACE, encodes a 521 amino acid protein homologous to human CREB3I2 (BBF2H7) and
This study aimed to investigate the efficacy and safety of oxcarbazepine tablet treatment of children with partial epilepsy.A total of 118 patients, who were 2-14 years old and newly diagnosed with pa
Transient global ischemia induces selective neuronal death in the CA1 area of the hippocampus and Amaurosis fugax, a phenomenon of a transient monocular visual loss.
This study aimed to observe the therapeutic effect of histamine 3 receptor antagonists in an animal model of neonatal hypoxic-ischemic encephalopathy, established in neonatal Wistar rats by ligation o
This study investigated the mechanisms of erythropoietin (Epo) and C-Epo, as neuroprotective treatments for stroke to determine the future clinical use of Epo and C-Epo.A total of 56 male mice were di
Accumulation of brain amyloid-β is a pathological feature of Alzheimers disease.Dyshomeostasis of bivalent metals such as zinc, iron and copper initiate amyloid-β deposition and the formation of senil
Our previous studies indicated that the transplantation of rat embryonic-derived neural stem cells (NSCs) overexpressing brain-derived neurotrophic factor (BDNF) (BDNF/NSCs) caused overexpression of B