The Mechanism of Transmembrane Permeation of Charged Methyl Guanidine

来源 :2013年上海市研究生学术论坛——计算生物学与系统生物学论坛 | 被引量 : 0次 | 上传用户：hzq1989aa

【摘要】

：

　　The mechanism of transmembrane ion permeation is studied using charged methyl guanidine as a model ion.With a widely applied reaction coordinate, our umbrel

【作者】

：

王昱焜

【机构】

：

上海交通大学生命科学学院

【出处】

：

2013年上海市研究生学术论坛——计算生物学与系统生物学论坛

【发表日期】

：

2013年7期

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

　　The mechanism of transmembrane ion permeation is studied using charged methyl guanidine as a model ion.With a widely applied reaction coordinate, our umbrella sampling results demonstrate a significant finite-size effect in small simulation systems and a serious hysteresis in large systems.

其他文献

玉米大斑病菌StHog1互作蛋白的筛选

由玉米大斑病菌(Setosphaeria turcica)引起的玉米大斑病是威胁玉米生产安全的重要病害之一,常造成严重的经济损失.探明调控病菌生长发育及致病性的信号转导途径、寻找作用于

会议

Computational Studies of Mechanistic Insight into Prostaglandin Synthases

　　Prostaglandins (PG) and thromboxane A2 are physiologically active substances derived from arachidonic acid.PGD2 and PGE2 synthases convert PGH2 to PGD2 and

会议

Prostaglandinsenzymatic reaction mechanismsdensity functional calculationsQM/

雷公藤内生放线菌多样性及活性评价

植物内生菌物种丰富、代谢产物结构类型多样,是寻找新活性物质的重要来源.从昆明、楚雄和大理等地的10份雷公藤样品(春、秋各5份)中获得了238株内生放线菌,经16S rRNA基因序

会议

Significant expression of pectinase and β-glucosidase by yeasts stocked at bank of fungi with biotec

The use of yeasts in biotechnological processes is indisputable and can be achieved through strategies that seek to select stored strains with particular charac

会议

Yeastspectinaseβ-glucosidasebiotechnologyMicoteca URM/Brazil

Network biology and its application to complex diseases

　　Non-smooth or even abrupt state changes exist during many biological processes, e.g.,cell differentiation processes, proliferation processes, or even diseas

会议

Su YAO Bacterial Community Diversity from high temperature Daqu of Sesame-flavor Liquor

The Sesame-flavor Liquor is one of innovative liquor types in China, which has been universally popular for its technology characteristics combined with multifo

会议

Sesame-flavor liquorhigh-temperature Daqubacterial community16S rDNA clonle l

基于基因组规模代谢网络模型系统解析与改造工业微生物代谢特性

微生物全基因组数据和其他组学数据的不断涌现为解析、调控和优化工业微生物生产性能提供新的眼界,但如何将这些海量、分散的组学数据与实际工业生产建立联系,从系统生物学角

会议

Bioinformatics Study Easy Come, Slow Go

近年来,生物信息学己成为生命科学领域中发展最为迅猛的学科之一,也深得青年学子们的青睐.然而,这一学科在实际应用和人才培养中的"软肋"日趋明显.此次报告将通过若干研究实

会议

利用理论计算研究复杂的酶催化机理一种新的中间体辅助催化机制的发现

　　BluB在维生素B12的生物合成过程中催化了关键的黄素分解反应,其产物是构建维生素B12的配体.由于维生素B12的重要生物功能以及它在科学发展史上的重要地位,BluB的相关研究

会议

Atomistic Mechanism of MicroRNA Translation Upregulation via Molecular Dynamics Simulations

　　MicroRNAs are endogenous 23-25 nt RNAs that play important gene-regulatory roles in animals and plants.Recently, miR369-3 was found to upregulate translatio

会议

The Mechanism of Transmembrane Permeation of Charged Methyl Guanidine

其他学术论文