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  5. Novel Zn-BTMPAMP complex for Cu-exchange in amyloid-β-Cu protects against copper-induced amyloid-β t

Novel Zn-BTMPAMP complex for Cu-exchange in amyloid-β-Cu protects against copper-induced amyloid-β t

来源 :The 5th International Symposium on Metallomics(第五届金属组学国际研讨会) | 被引量 : 0次 | 上传用户：xiang879154
【摘 要】
：
Abnormal interactions of copper and zinc ions with amyloid-β(Aβ)peptide play a critical role in the pathogenesis of Alzheimers disease(AD),which participating in the aggregation process of Aβ and in t
【作 者】
：
Chuangji Liu Limin Yang Qiuquan Wang 
【机 构】
：
Department of Chemistry,the MOE Key Lab of Spectrochemical Analysis & Instrumentation,Xiamen Univers
【出 处】
：
The 5th International Symposium on Metallomics(第五届金属组学国际研讨会)
【发表日期】
：
2015年7期
【关键词】
：
Alzheimer's disease amyloid-β Cu/Zn complex metal-swap 
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　　Abnormal interactions of copper and zinc ions with amyloid-β(Aβ)peptide play a critical role in the pathogenesis of Alzheimers disease(AD),which participating in the aggregation process of Aβ and in the generation of reactive oxygen species(ROS).
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