Transmembrane Potential enhances Direct Translocation of Cell-Penetrating Peptides

• 作 者: Xinli Gao Song Hong Tongtao Yue Zhiping Liu Jure Dobnikar Xianren Zhang
• 机 构: StateKeyLaboratoryofOrganic-InorganicComposites,BeijingUniversityofChemicalTechnology,Beijing100029,
• 出 处: 中国化学会2016软物质理论计算与模拟会议
• 发表日期: 2016年8期
• 关键词: Cell-penetrating peptides membrane membrane potential translocation

　　Cell-penetrating peptides(CPPs)are shown experimentally to be capable of entering cells in an energy-independent pathway of direct translocation,which is complementary to endocytosis and featured by the rapid uptake,making CPPs a fascinating drug delivery agent.