【摘 要】
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Motivation: One of the most promising applications of biosynthetic methods is to produce chemical products of high value from the ready-made chemicals.To explore the biosynthetic potentials of a chemi
【机 构】
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Key Laboratory of Combinatorial Biosynthesis and Drug Discovery(Wuhan University),Ministry of Educat
【出 处】
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第八届国际分子模拟与信息技术应用学术会议
论文部分内容阅读
Motivation: One of the most promising applications of biosynthetic methods is to produce chemical products of high value from the ready-made chemicals.To explore the biosynthetic potentials of a chemical as a synthesis precursor,biosynthetic databases and related chemoinformatics tools are urgently needed.In the present work,a web-based tool,BioSynther,is developed to explore the biosynthetic potentials of precursor chemicals using BKM-react,Rhea,and more than 50000 inhouse RxnFinder reactions manually curated.BioSynther allows researchers to explore biosynthetic potentials,through so far known biochemical reactions,step by step interactively,which could be used as a useful tool in metabolic engineering and synthetic biology.
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