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Synopsis We have measured the absolute double-differential cross sections (DDCSs) for electron emission in ionization of H2O molecules under the impact of fast (energy: 48-72 MeV) O8+ ions.The DDCS spectra are compared with the continuum distorted-wave eikonal initial-state calculations in both prior and post forms.The overall agreement with the CDW-EIS model is quite good as far as the energy dependence is concerned.The prior form of the model is found to provide a better understanding of the data compared to the post version.