Na+-Ca2+ exchanger,leak K+ channel and HCN channel co-mediate the histamine-induced excitation on ra

来源 :The 6th FAONS Congress and 11th Biennial Conference of CNS(第 | 被引量 : 0次 | 上传用户：ie286

【摘要】

：

Anti-histaminergic drugs have traditionally been used to treat vestibular disorders in clinic.As a potential central target for anti-histaminergic drugs,inferior vestibular nucleus(IVN)is the largest

【作者】

：

Lei Yu Xiao-Yang Zhang Shu-Liang Cao Shi-Yu Peng Jing-Ning Zhu Jian-Jun Wang

【机构】

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State Key Laboratory of Pharmaceutical Biotechnology and Department of Biological Science and Techno

【出处】

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The 6th FAONS Congress and 11th Biennial Conference of CNS(第

【发表日期】

：

2015年3期

【关键词】

：

Histamine Inferior vestibular nucleus H1 receptors H2 receptors Ionic mechanisms

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　　Anti-histaminergic drugs have traditionally been used to treat vestibular disorders in clinic.As a potential central target for anti-histaminergic drugs,inferior vestibular nucleus(IVN)is the largest nucleus in the central vestibular nuclear complex and considered responsible for vestibular-autonomic responses and integration of vestibular,multisensory and cerebellar signals.

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Na+-Ca2+ exchanger,leak K+ channel and HCN channel co-mediate the histamine-induced excitation on ra

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