Hydrogen sulfide antagonizes Formaldehyde-induced neurotoxicity by inhibition of autophagy via upreg

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  Formaldehyde (FA) has neurotoxicity and we have previously demonstrated that hydrogen sulfide (H2S),the third gasotransmitter,antagonizes FA-induced neurotoxicity.However,the exact mechanisms underlying this protection remain largely unknown.It has been confirmed that excessive autophagy leads to apoptosis and cytotoxicity eventually and that leptin involves in neuroprotective regulating.
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