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There have been numerous studies concerning the associations of angiotensin-converting enzyme (ACE) gene insertion/ deletion (I/D),angiotensin II receptor 1 (AT1R) gene A1166C,and endothelial nitric oxide synthase (eNOS) gene 4b/a polymorphisms with risk of pregnancy hypertensive disorders (PHDs).However,the results are inconsistent.A total of 83 eligible studies (10,354/18,446 cases/controls) were included in this meta-analysis.Pooled odds ratios with corresponding 95 %confidence intervals were used to calculate these associations.