Hard Tissue Formation of STRO-1 Selected Rat Dental Pulp Stem Cells In Vivo

• 作 者: Xuechao Yang X.Frank Walboomers Jeroen J.J.P.van den Beucken Zhuan Bian Mingwen Fan John A.Jansen
• 机 构: Department of Periodontology and Biomaterials,Radboud University Nijmegen Medical Centre,Nijmegen,Th
• 出 处: 全球华人口腔医学大会暨2010中国国际口腔医学大会
• 发表日期: 2010年4期

　　The objective of this study was to examine hard tissue formation of STRO-1 □selected rat dental pulp-derived stem cells,seeded into a calcium phosphate ceramic scaffold,and implanted subcutaneously in mice.Previously,STRO-1 selection was used to obtain a mesenchymal stem cell progenitor subpopulation from primary dental pulpderived stem cells.In the current study,these cells were cultured with three different media:"BMP-plus" medium containing dexamethasone and 100 ng =mL of rhBMP-2,"odontogenic" medium containing dexamethasone,and "control" medium without supplements.