Objective: Combined blockade of T-cell checkpoints by NIVO and IPI demonstrated a high objective response rate (ORR), promising overall survival (OS) and a manageable safety profile in pts with advanc
Objective: To observe and analyze the retinopathy associated with high doses of interferon α-2b therapy in patients with melanomas of the skin.Method: Eighteen patients with melanomas of the skin whos
目的: Everolimus, an oral mTOR inhibitor, has shown minimal activity as a single agent in patients with metastatic melanoma unselected for potential predictive biomarkers (J Clin Oncol 24: 463s, 2006)。
目的: BRAF/NRAS mutations are predictors of poor prognosis in melanoma.High-dose interferon (HDI) is the only drug approved by FDA as adjuvant therapy in high risk resected melanomas.
Objective: This in vivo study on nude mice bearing SKOV-3 human ovarian carcinoma xenografts aims to show that intravenously administrated 30-nm CoFe2O4@BaTiO3 coreshell magneto-electric nanoparticles
Objective: Activating mutations in the gene encoding EGFR occur primarily in non-small cell lung cancer (NSCLC) and result in constitutive activation of the kinase activity of the EGFR protein, thereb