【摘 要】
：
A deoxypodophyllotoxin derivative (DPD) modified in the D-ring was synthesized and evaluated its anti-tumor activity in the HeLa cells.DPD showed anti-proliferative activity in a dose and time-dependa
【机 构】
：
Hebei University, College of Life Science, Key Laboratory of Medicinal Chemistry and Molecular Diagn
【出 处】
：
中国化学会第十届全国天然有机化学学术会议
论文部分内容阅读
A deoxypodophyllotoxin derivative (DPD) modified in the D-ring was synthesized and evaluated its anti-tumor activity in the HeLa cells.DPD showed anti-proliferative activity in a dose and time-dependant manner and less plasma membrane damage than etoposide using lactate dehydrogenase (LDH) assay.
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