Noradrenergic activity regulated dexamethasone-induced increase of 5-HT3 receptors-mediated glutamat

• 作 者: YingmeiFu[1]ShunyingYu[1]XiaoyunGuo[1]KerunGao[1]YiDong[2]
• 机 构: Shanghai Mental Health Center,Shanghai Jiao Tong University School of Medicine,Shanghai China
• 出 处: 中国神经科学学会精神病学基础与临床分会第九届学术会议
• 发表日期: 2012年期

　　Objective: Stress hormone, glutamatergic system, serotonergic system and the noradrenergic system are involved in depressive disorders.However, the relationship among these is still unclear.The present study examined the effect of dexamethasone (DEX) on the presynaptic glutamate release of synaptosomes from rat prelimbic cortex.