The local corticotropin-releasing hormone receptor 2 signalling pathway partly mediates hypoxia-indu

• 作 者: 熊艳蕾[1]ZhuanQu[2]NanChen[1]HuiGong[1]MintaoSong[1]XuequnChen[2]JizengDu[2]ChengliXu[1]
• 机 构: 中国医学科学院基础医学研究所病理生理学系,北京,100005
• 出 处: 中国生理学会第24届全国会员代表大会暨生理学学术大会
• 发表日期: 2014年期

　　Our objective was to investigate the mechanisms by which the endogenous CRHR2 in white adipose tissue (WAT) regulates metabolic activities associated with lipogenesis and lipolysis under continuous exposure to hypoxia.We found that hypobaric hypoxia at a simulated altitude of 5,000m significantly reduced the body weight,food intake,and WAT mass of rats.