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为了解肺结核病人耐药情况、流行情况、耐药特点及有关影响疗效的因素,从中找出问题并探讨解决的方法,我们从1998年以来共选出83例治疗的耐药结核病人进行耐药性测试。 实验方法:入选病例83株结核分枝杆菌用绝对浓度法测试药物敏感性,对INH、SM、RFP、PZA和EMB进行药物敏感性试验。 结果:1.单耐药者:耐H 62例,占74.2％;耐R 60例,占72.3％;耐E 52例,占62.6％;耐Z 26例,占31.3％;耐S 4例,占4.8％。2.联合耐药者:耐HR 6例,占7.2％;耐HRE 24例,占28.9％;耐HRZ1例,占1.2％,耐HREZ
In order to find out the drug resistance, epidemic, drug resistance characteristics of TB patients and the factors affecting their efficacy, find out the problems and explore the solutions. From 1998, we selected 83 cases of drug-resistant TB patients for resistance Sex test. Experimental methods: Selected cases of Mycobacterium tuberculosis by absolute concentration method to test drug sensitivity, INH, SM, RFP, PZA and EMB drug sensitivity test. Resistant to E 2 cases, accounting for 62.6%; resistant to Z 26 cases, accounting for 31.3%; resistant to S 4 cases, Accounting for 4.8%. 2. Combined resistance: HR 6 cases, accounting for 7.2%; HRE resistant to 24 cases, accounting for 28.9%; HRZ1 cases, accounting for 1.2%, resistant to HREZ