Silica nanoparticles induce oxidative stress,inflammation and endothelial dysfunction viaactivation

• 作 者: CaixiaGuo;YinyeXia;PiyeNiu;LizhenJiang;JunchaoDuan;YangYu;XianqingZhou;YanboLi;ZhiweiSun;
• 机 构: School of Public Health,Capital Medical University,Beijing,100069,P.R.China
• 出 处: 全国卫生毒理学术研讨会
• 发表日期: 2014年期

　　Despite the widespread application of silica nanopartieles (SiNPs) in industrial,commercial,and biomedical fields,their response to human cells has not been fully elucidated.Overall,little is known about the toxicological effects of SiNPs on the cardiovascular system.In this study,SiNPs with a 58 nm diameter were used to study their interaction with human umbilical vein endothelial cells,HUVECs.