Characterization of Vibrio parahaemolyticus isolated from Patients in Zhoushan of China

• 作 者: HonglingWang[1]XiaoyangTang[1]JiabeiChen[1]LijunHuang[2]Yi-ChengSu;
• 机 构: Key Laboratory of Health Risk Factors for Seafood of Zhejiang Province,Zhoushan 316021,China
• 出 处: 第七届传染病防控基础研究与应用技术论坛
• 发表日期: 2016年期

　　Vibrio parahaemolyticus has emerged as a common foodborne pathogen of global concern.This study collected 107 strains of V.parahaemolyticus from active surveillance hospitals in Zhoushan during 2013 to 2014 and investigated their serotypes,virulence genes(tdh,trh and ORF8),antimicrobial resistance and genotypes.The dominant serotypes of the 107 clinical strains were O3:K6,O4:K8 and O4:KUT with 87.9 and 3.7%of the strains carrying virulence genes tdh and trh,respectively.Molecular typing by pulsed-field gel electrophoresis showed divergence among the clinical strains.Analysis of resistance of the strains to antibiotics revealed high resistance of the clinical isolates to Ampicillin(100%),Piperacillin(30.84%),Cephalothin(16.82%),Cefuroxime(4.67%),Streptomycin(3.74%),Cefazolin(1.87%),Cefoxitin(1.87%),Ceftazidime(0.93%),Aztreonam(0.93%),and Kanamycin(0.93%)with 49.5%of the isolates showing resistant to two or more antibiotics grouped in 10 different resistance patterns.Ongoing surveillance of V.parahaemolyticus in diarrhea patients is a public health priority and is useful in conducting risk assessment of foodborne illnesses caused by V.parahaemolyticus.